Researchers are working on an “on and off” switch to improve the safety and efficacy of chimeric antigen receptor (CAR) T-cell therapy and counter...
News
Dr. Madduri on Eligibility for CAR T-Cell Therapy in Myeloma
Deepu Madduri, MD, assistant professor, Mount Sinai Hospital, discusses eligibly criteria for patients with multiple myeloma to receive chimeric...
Want to make better T-cell therapies? First, figure out how they work
These man-made cancer-fighting molecules are infinitely variable, like a set of Legos, each one constructed to allow a patient’s immune cells to...
First in-depth profile of CAR T-cell signals suggests how to improve immunotherapy
CAR T-cell therapy, which reprograms immune cells to fight cancer, has shown great promise in people with some blood cancers who have not responded...
Selinexor and Multiple Myeloma
There are various treatment options for patients with multiple myeloma (MM), including autologous hematopoietic stem cell transplantation (HSCT),...
Georgia woman hopes experimental “living” cancer therapy will stop her myeloma
For 48-year old Atlanta mom, wife and dog groomer Cheri Letts, the realization she was sick came slowly. "I was starting to feel rundown, and it...
Advances Could Lead to Curative Strategies in Myeloma
There are currently 10 FDA-approved treatments in the multiple myeloma space; however, a more personalized therapy could be key to finding a cure,...
Treatment options for refractory/relapsed multiple myeloma: an updated evidence synthesis by network meta-analysis
Background: The refractory/relapsed multiple myeloma (RRMM) remains a big clinical challenge, due to its biological and clinical complexity. Leading...
Two molecules offer great potential to combat cancer and chronic infections
To fight viral infections, your immune system calls on CD8 T cells to kill the infected cells. The CD8 T cells can also be used in immunotherapy...
New guidelines help ensure optimal outcomes for children treated with CAR-T Cell Therapy
While chimeric antigen receptor (CAR)-T cell therapy has demonstrated positive response rates in children with relapsed and/or refractory...
Could athersys play a role in the progression of CAR-T Therapy?
One of newest and most exciting approved treatments for cancer is the use of CAR-T therapy. CAR stands for chimeric antigen receptor and T stands...
Advances in T cell therapy may fight cancer without side effects
The human immune system is truly a wonder. It plays a critical role in our body’s defense to invading disease. Like a home security system, it is on...